Daily topical cream
Estradiol Cream
A daily estradiol cream that may help relieve menopausal symptoms such as hot flashes, night sweats and sleep changes.
Plan
- Start a consultation
Topical cream
$159 /mo, billed every 28 days
Renews automatically every 28 days (13 times a year) until you cancel. You're charged only after you confirm checkout; cancel anytime from your dashboard.
- How often
- Once a day
- Prescription
- Required, after clinician review
- Lab work
- Not listed as required
- Delivery
- Two-day shipping
Potential benefits
With a clinician's guidance, Estradiol Cream may help support:
- Hot flashes and night sweats
- Sleep and mood
- Vaginal dryness
- Bone health
Individual results vary and are not guaranteed.
Who it's for
- Women in perimenopause or menopause whose clinician determines it is appropriate
- With an intact uterus, progesterone is typically added to protect the uterine lining
- Located in Florida at the time of your visit
Lab requirements
No lab work required. Optional panels can be used to track progress.
How treatment works
- Create an accountChoose this treatment and create your account.
- Complete your intakeAnswer health-history and goals questions in the secure clinical platform.
- Clinician reviewA licensed clinician reviews your intake and labs, if required.
- Video visit if neededDepending on your history and Florida rules, the clinician may require a short video visit.
- Pharmacy and shippingIf prescribed, a licensed pharmacy prepares your order and it ships with two-day delivery.
- Ongoing careOptional check-ins with your clinician for dose adjustments and follow-up.
Consultation requirements
You complete an online health history first. A licensed clinician reviews it, and may require a short video visit depending on your history and where you live, before deciding whether to prescribe.
All prescription treatments require evaluation and authorization by an appropriately licensed medical professional. A clinician may decline to prescribe or recommend another option.
Pricing and billing
| Option | Price | Billing frequency |
|---|---|---|
| Topical cream | $159 /mo | billed every 28 days |
Included
- Review of your intake by a licensed clinician and a prescription only when appropriate
- Compounded estradiol cream, prepared by a state-licensed pharmacy
- Discreet two-day shipping each cycle
- Messaging with the care team for questions and dose adjustments
- Pause, delay or cancel your plan at any time
Additional fees
- No additional fees listed.
- No separate consultation fee is listed.
Automatic renewal: if you're prescribed estradiol cream and confirm checkout, your plan renews every 28 days at the price you chose ($159 for topical cream) until you cancel. You can cancel online from your dashboard at any time; cancellation stops future renewals. See the refund and cancellation policy.
Safety information
Common side effects
- Nausea
- Mood changes
Avoid skin contact with others at the application site until absorbed.
This is a compounded medication, prepared by a state-licensed pharmacy for you from a clinician's prescription. Compounded estradiol is not FDA-approved, and FDA does not review compounded drugs for safety, effectiveness or quality.
Tell your clinician about all medications, supplements and conditions. If you have a medical emergency, call 911.
Questions about Estradiol Cream
Do I need a prescription?
Yes. Nothing ships until a licensed clinician has reviewed your health history and decided the treatment is appropriate for you. Some patients are asked to join a short video visit first.
How does billing work?
Plans renew automatically every 28 days at the price shown, which is 13 billing cycles a year. You'll see the amount and renewal date before you confirm, and you can cancel online from your dashboard.
Can I cancel anytime?
Yes. Cancel from your dashboard in the same place you signed up. Cancelling stops future renewals; it doesn't refund a cycle that has already been prepared or shipped. Full terms are in our refund and cancellation policy.
What if I have side effects?
Message the care team through your patient portal. For severe or unexpected symptoms, seek medical care right away, and call 911 in an emergency.
Ready to talk to a clinician?
Request a consultation for Estradiol Cream. You won't be charged until you confirm checkout.